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CD81 (Mouse/Rat) Recombinant Monoclonal Hamster Antibody (24MS04.81) – Biotium Choice

CD81 (24MS04.81) is a validated recombinant hamster monoclonal antibody that recognizes the tetraspanin protein CD81 from mouse and rat. The antibody belongs to the Biotium Choice list of select antibodies that have been formulated and validated in-house for optimal performance.

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100 tests
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Product Description

CD81 (24MS04.81) is a recombinant hamster monoclonal antibody that recognizes the tetraspanin protein CD81 from mouse and rat. This antibody belongs to the Biotium Choice list of select antibodies that have been formulated and validated in-house for optimal performance. This antibody has been validated in flow cytometry and immunofluorescence microscopy. The antibody is available purified and BSA-free.

CD81 is a 26 kD non-glycosylated member of the tetraspanin superfamily (TM4SF), also known as TAPA-1. CD81 is expressed on T and B cells, NK cells, dendritic cells, thymocytes, endothelial cells, and fibroblasts. CD81 induces B cell adhesion via the VLA-4 integrin and has been shown to play a role in early T cell development. CD81 associates with several other cell-surface proteins in a multimolecular complex, including CD19, CD21, CD20, CD37, CD53, and CD82 in B cells, and CD4, CD8 and CD82 in T cells.

Tetraspanin proteins CD9, CD63, and CD81, are the most common proteins used as exosome markers. Tetraspanins are plasma membrane proteins with many proposed functions, including activation and sorting of other membrane proteins. They are also thought to play a role in the targeting of proteins to multivesicular bodies (MVBs) and exosomes. These tetraspanins are broadly expressed on many cell types and can therefore be detected on many types of exosomes, but their expression levels vary depending on the cell type of origin.

Biotium also offers Biotium choice recombinant antibodies against mouse CD9 (24MS04.9) and human CD81 (2304.81).

View our full catalog of Biotium Choice antibodies, optimized and validated for the best results in flow cytometry.

Exosome Stains and Antibodies

Biotium also offers ExoBrite™ CD81 Flow Antibody and ExoBrite™ CD81 Western Antibody that are validated for optimal detection of isolated exosomes by flow cytometry or western blotting. Learn more about our products for exosome research.

ConjugationEx/EmConc.SizeCatalog No.Dye Features
CF®405M416/452 nm100 ug/mL25 tests (125 uL)P017-405M-125CF®405M Features
100 tests (500 uL)P017-405M-500
CF®488A490/516 nm100 ug/mL25 tests (125 uL)P017-488A-125CF®488A Features
100 tests (500 uL)P017-488A-500
CF® 568562/584 nm100 ug/mL25 tests (125 uL)P017-568-125CF®568 Features
100 tests (500 uL)P017-568-500
CF® 647Plus652/668 nm100 ug/mL25 tests (125 uL)P017-647P-125CF®647Plus Features
100 tests (500 uL)P017-647P-500
Purified (BSA-free)N/A5 mg/mL1 mgP017-1MG
5 mgP017-5MG
 

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